The approach involves the use of highly immunogenic molecule like the hemocyanin for non-specific immunostimulation (NSI) or active specific immunostimulation (ASI) using conjugate vaccines, wherein the tumor (disease) specific antigens are covalently bound to carrier protein like KLH and the product used in human clinical studies. Such products are termed “vaccines”. BioVision’s KLH subunits powder has major advantages associated with it, in terms of flexibility of use and the choice of buffer in early developmental studies. These subunits are highly pure and have low endotoxin content.
DESCRIPTION :
Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been in use as an immunological reagent for many years. It is used as a carrier protein for antibody production against antigens. Recent advances in immunology and the role immune system plays in diseases have opened a whole new era of product development activities aimed at developing novel therapeutics which is aimed at teaching the body’s immune system to fight diseases like cancer, AIDS, etc.
SPECIFICATIONS
Protein/Peptide Name
Hemocyanin-Keyhole Limpet (KLH)
Protein Synonyms
keyhole limpett hemocyanin,KLH,hemocyanin,Megathura crenulata hemocyanin
Species
Giant keyhole limpet
Form
Powder
Molecular Weight
350 and 390 kDa (Two main characteristic bands co-migrating with ferritin)
Reconstitution Instructions
Resuspend in sterile water to a 1 mg/ml concentration
Storage Conditions
2…8 °C
Shipping Temperature
Gel pack
Molecular Weight
350 and 390 kDa (Two main characteristic bands co-migrating with ferritin)
megathura
Datasheet
Cat # +Size
6286-1
Size
1 mg
Alternate Name
KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin
Gene Symbol
KLH
Source
Megathura crenulata, Giant keyhole limpet
Appearance
Lyophilized protein
Physical Form Description
Freeze Dried
Molecular Weight
350 and 390 kDa (Two main characteristic bands co-migrating with ferritin)
Purity by SDS-PAGE
≥ 95%
Reconstitution Instructions
Resuspend in sterile water to a 1 mg/ml concentration
Handling
Centrifuge the vial prior to opening.
Storage Conditions
2-8°C
Shipping Conditions
Gel Pack
USAGE
For Research Use Only! Not to be used in humans
Recombinant Megathura crenulata Hemocyanin A chain
MBS7072452-05mgEColi
MyBiosource
0.5mg(E-Coli)
EUR 700
Recombinant Megathura crenulata Hemocyanin B chain
MBS7073467-005mgBaculovirus
MyBiosource
0.05mg(Baculovirus)
EUR 875
Recombinant Megathura crenulata Hemocyanin B chain
MBS7073467-005mgEColi
MyBiosource
0.05mg(E-Coli)
EUR 490
Recombinant Megathura crenulata Hemocyanin B chain
MBS7073467-005mgYeast
MyBiosource
0.05mg(Yeast)
EUR 695
Recombinant Megathura crenulata Hemocyanin B chain
MBS7073467-02mgEColi
MyBiosource
0.2mg(E-Coli)
EUR 640
Recombinant Megathura crenulata Hemocyanin B chain
MBS7073467-05mgEColi
MyBiosource
0.5mg(E-Coli)
EUR 695
Recombinant Megathura crenulata Hemocyanin 2-c chain
MBS1220450-002mgBaculovirus
MyBiosource
0.02mg(Baculovirus)
EUR 1290
Recombinant Megathura crenulata Hemocyanin 2-c chain
MBS1220450-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 970
Recombinant Megathura crenulata Hemocyanin 2-c chain
MBS1220450-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 1085
Recombinant Megathura crenulata Hemocyanin 2-c chain
MBS1220450-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 1130
Recombinant Megathura crenulata Hemocyanin 2-c chain
MBS1220450-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 1230
Keyhole Limpet Hemocyanin (Megathura Crenulata) Carrier protein
KLH51-R10
Alpha Diagnostics
10 mg
EUR 242.4
Keyhole Limpet Hemocyanin (Megathura Crenulata) Carrier protein
KLH51-R100
Alpha Diagnostics
100 mg
EUR 489.6
Keyhole Limpet Hemocyanin (KLH, Megathura Crenulata, >98%, low endotoxin, azide free)
KLH52-R-LE-1
Alpha Diagnostics
1 mg
EUR 270
Megathrin A
TBZ1612
ChemNorm
unit
Ask for price
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Recombinant Bacillus megaterium Protein teg (teg)
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0.02mg(E-Coli)
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Recombinant Bacillus megaterium Protein teg (teg)
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0.02mg(Yeast)
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Recombinant Bacillus megaterium Protein teg (teg)
MBS1045116-01mgEColi
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0.1mg(E-Coli)
EUR 1015
Recombinant Bacillus megaterium Protein teg (teg)
MBS1045116-01mgYeast
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0.1mg(Yeast)
EUR 1120
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MBS1280153-002mgBaculovirus
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0.02mg(Baculovirus)
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Recombinant Bacillus megaterium Protein ArsC (arsC)
MBS1280153-002mgEColi
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0.02mg(E-Coli)
EUR 645
Recombinant Bacillus megaterium Protein ArsC (arsC)
MBS1280153-002mgYeast
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0.02mg(Yeast)
EUR 815
Recombinant Bacillus megaterium Protein ArsC (arsC)
MBS1280153-01mgEColi
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0.1mg(E-Coli)
EUR 750
Recombinant Bacillus megaterium Protein ArsC (arsC)
MBS1280153-01mgYeast
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0.1mg(Yeast)
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Recombinant Bacillus megaterium Protein sspF (sspF)
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0.02mg(Baculovirus)
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Recombinant Bacillus megaterium Protein sspF (sspF)
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Recombinant Bacillus megaterium Protein sspF (sspF)
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0.02mg(Yeast)
EUR 735
Recombinant Bacillus megaterium Protein sspF (sspF)
MBS1198857-01mgEColi
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0.1mg(E-Coli)
EUR 645
Recombinant Bacillus megaterium Protein sspF (sspF)
MBS1198857-01mgYeast
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0.1mg(Yeast)
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Recombinant Bacillus megaterium Bacillolysin (nprM)
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0.02mg(Baculovirus)
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Recombinant Bacillus megaterium Bacillolysin (nprM)
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0.02mg(E-Coli)
EUR 845
Recombinant Bacillus megaterium Bacillolysin (nprM)
MBS1222003-002mgYeast
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0.02mg(Yeast)
EUR 985
Recombinant Bacillus megaterium Bacillolysin (nprM)
MBS1222003-01mgEColi
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0.1mg(E-Coli)
EUR 1015
Recombinant Bacillus megaterium Bacillolysin (nprM)
MBS1222003-01mgYeast
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0.1mg(Yeast)
EUR 1120
Recombinant Bacillus megaterium Bacillolysin (nprM)
MBS1217128-002mgBaculovirus
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0.02mg(Baculovirus)
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